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This gene encodes a transcription issue that belongs towards the homeobox gene household. Genes of this loved ones are very conserved among the vertebrates and essential for vertebrate embryonic development. This gene has actually been implicated in fetal pores and skin development and cutaneous regeneration.

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In mice, the same gene was demonstrated to exhibit temporal and spatial colinearity in the principle physique axis on the embryo, but was not expressed while in the secondary axes, which suggests functions in overall body patterning together the axis. This gene and other HOXB genes kind a gene cluster on chromosome seventeen from the 17q21-22 region.[six]

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